Topical composite hydrogel incorporating human amniotic membrane and spidroin for the treatment of chronic wounds in diabetes mellitus

Abstract\\r\\nBackground and purpose: Traditional diabetic chronic skin wound dressings often lack the bioactivity\\r\\nrequired to promote regeneration in these complex wounds. The use of human amniotic membrane (hAM)\\r\\nhas been identified as a promising natural option for diabetic skin wound regeneration, but hAM is\\r\\nsusceptible…